Thursday, October 24, 2019

Screening and Treatment for Iron Deficiency in HFrEF with Ferric Carboxymaltose





Clinical practice update on heart failure 2019:pharmacotherapy, procedures, devices andpatient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology Petar M. Seferovic1, Piotr Ponikowski2, Stefan D. Anker3*, Johann Bauersachs4, Ovidiu Chioncel5, John G.F. Cleland6, Rudolf A. de Boer7, Heinz Drexel8, Tuvia Ben Gal9, Loreena Hill10, Tiny Jaarsma11, Ewa A. Jankowska2, Markus S. Anker12, Mitja Lainscak13, Basil S. Lewis14, Theresa McDonagh15, Marco Metra16, Davor Milicic17, Wilfried Mullens18, Massimo F. Piepoli19, Giuseppe Rosano20, Frank Ruschitzka21, Maurizio Volterrani22, Adriaan A. Voors7, Gerasimos Filippatos23, and Andrew J.S. Coats24*


Ferric Carboxymaltose

Monday, October 21, 2019

Anticoagulation in Concomitant Chronic Kidney Disease and Atrial Fibrillation

• The decision to initiate OAT poses a clinical conundrum in patients with coexisting AF and advanced CKD.
• In CKD, several pathophysiological factors result in a progressively increased risk of both ischemic stroke and hemorrhage as renal function declines, irrespective of OAT.
• The limited available data suggests that DOACs should generally be favored over VKAs in view of their probable increased safety and efficacy in CKD, with a lower risk of vascular calcification and anticoagulant-associated nephropathy.
• Until dedicated RCTs are completed to define optimal management, clinical decision-making should be informed by the limited data available, which necessitates individualization and physician-patient collaboration.


Sunday, October 20, 2019

Diagnosis and Treatment of Pulmonary Embolism

The recent European Society of Cardiology (ESC) and European Respiratory Society (ERS) Joint release of the Diagnosis and Management of Acute Pulmonary Embolism Guidelines (2019) highlight a number of changes in class level recommendations as compared to the 2014 version, as well as new guideline recommendations. Among these, a Class IIa recommendation for multidisciplinary management of patients means that awareness of the emerging trends in PE management is crucial.

Phillip Green, MD (Columbia University Medical Center) provides an in-depth analysis of Pulmonary Embolus Response Team (PERT) protocols in Contemporary Treatment for Pulmonary Embolism in the CurrentMD platform. 


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Fourth Universal Definition of Myocardial Infarction

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